Researchers have found that increasing the levels of this vitamin improve the symptoms of Crohn’s disease, one recent study found a “significant interaction between vitamin D levels and Crohn’s disease susceptibility, as well as a significant association between vitamin D levels and genotype.”
Patients were found to have significantly reduced serum vitamin D levels.
Researchers analyzed 7 DNA sequence variations, and two of them showed a strong link between vitamin D levels in those with Crohn’s, and four variants were found to be related to vitamin D levels among controls.
This indicates that vitamin D influences genetic expression associated with Crohn’s disease, and while its deficiency can aggravate the symptoms, its correction improves them.
Scientists have also found that vitamin D supplementation lowers pain and depression in diabetic women. PsychCentral explains:
“The investigators set out to determine how vitamin D supplementation might affect women with type 2 diabetes who were also suffering from depression.
At the beginning of the study, 61 percent of women reported neuropathic pain, such as shooting or burning pain in their legs and feet, and 74 percent had sensory pain, such as numbness and tingling in their hands, fingers, and legs.
During the course of the study, the participants took a 50,000 IU vitamin D2 supplement every week for 6 months. By the end of the study, the women’s depression levels had significantly improved following the supplementation.
Furthermore, participants who suffered from neuropathic and/or sensory pain at the beginning of the study reported that these symptoms decreased at 3 and 6 months following vitamin D2 supplementation.”
The lead researcher Todd Doyle, Ph.D. claims that vitamin D supplementation “is a promising treatment for both pain and depression in type 2 diabetes.”
Yet, you should choose D3 over D2, as in the long term, it might do more harm than good.
Drisdol is a synthetic form of vitamin D2, which is often prescribed by doctors. It is made by irradiating fungus and plant matter and is far from D3, the type our bodies produce in response to the sun or safe tanning bed exposure.
A 2012 meta-analysis by the Cochrane Database, analyzed the mortality rates for two groups of people, the first supplemented their diets with D2, and the second with D3.
Researchers found great differences between the groups. They evaluated the findings of 50 randomized controlled trials, which involved a total of 94,000 participants, and found that:
- A 2% relative risk increase among those who used D2
- A 6% relative risk reduction among those who used vitamin D3
This shows the importance of vitamin D in the treatment of type 2 diabetes. Moreover, research has shown that almost 60 percent of type 2 diabetics lack this vitamin.
Another study has shown that there is “a strong additive interaction between abdominal obesity and insufficient 25(OH)D in regard to insulin resistance.”
Researchers maintain that 47 percent of the increased risks of insulin resistance are due to the interaction between insufficient vitamin D levels and a high body mass index (BMI).
Diabetes Care published another study which showed that vitamin D supplements help in the treatment of type 2 diabetes mellitus in people with pre-diabetes.
Participants who had the highest vitamin D levels had a 30 percent lower risk to develop diabetes during the three-year evaluation period.
Furthermore, a recent Science World Report emphasized the recommendation by British breast cancer surgeon, Professor Kefah Mokbel, who suggests that women should take daily vitamin D supplements to reduce their risk of breast cancer. The featured article said:
“Prof. Mokbel has also requested Jeremy Hunt, the Health Secretary, to make [vitamin D] pills freely available as this would result in saving about a 1,000 lives annually.
‘I am calling for all women from the age of 20 to be given free vitamin D supplements on the NHS because it is effective in protecting against breast cancer,’ Prof. Mokbel said.